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Structural Biology Research Engineer for 3D Bio Molecular Modeling

Structural Biology Research Engineer for 3D Bio Molecular Modeling

The Institute

The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.

In April 2021, the Centre for Genomic Regulation (CRG) received the renewal of the 'HR Excellence in Research' Award from the European Commission. This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code).

Please, check out our Recruitment Policy

The role

The CRG is seeking for a 3D Molecular Modeller to join Dr. Serrano’s lab. The principal role of the position is the in silico design of biological molecules for the treatment of human diseases by means of in-house tools as FoldX and ModelX. The candidate will also be leading a subgroup within Luis Serrano’s laboratory composed of structural biologists and software engineers involved in the design, development, maintenance, distribution and scientific validation of the mentioned CRG proprietary software.

About the group

The design of biological systems group is aiming to the quantitative understanding of biological systems and predicting systemic features with the hope to rationally design and modify their behaviour. This applies to any system comprising biological components that is more than the mere sum of its components, or, in other words, the addition of the individual components results in systemic properties that could not be predicted by considering the components individually. By achieving this objective, we are aiming at new global understanding and treatment of human diseases by the design of immune modulatory molecules. For this purpose in the group it is developed on one hand new software and theoretical approximations to understand complex systems and on the other they do experiments to validate our predictions. Multidisciplinary profiles are requested for that purpose in order to fill the gap between different challenges arising from that approach.

You can find more information about the group and their research projects on their website:


Whom would we like to hire?

Professional experience

Must Have

• You have a strong background in Structural Biology and experience developing HPC methods
• You have more than 5 scientific publications related to the fields in international high impact journals as first or last author
• You have strong knowledge about DNA/RNA/Protein Stability and Interactions
• You have experience leading and supervising teams
• You have more than 5 years managing OOP projects
• You have experience as a software Designer using C/C++/SQL technologies, either as an Analyst or as an Engineer in Industry
• You have experience at Industry as software engineer and experience releasing portable multiplatform software

Desirable but not required/ Nice to have

• You have experience with analytical tools and intuition for software development
• You have mind debugging capabilities

Education and training

• You hold a PhD in Organic Chemistry, Biochemistry or similar
• You are a Software engineer by training


• You are proficient in English

Technical skills

• You have advanced OOP skills (Design Patterns, optimization and leak purification tools)
• You have high experience in C and SQL database tuning
• You are highly experience in C++/SQL on Unix
• You are use to work in big software development projects
• You have experience creating portable and multiplatform solutions without containers


• You have highly developed organization skills
• You have team managing skills
• You have developed communication skills
• You are independent, creative and efficient

The Offer – Working Conditions

• Contract duration: Permanent position.
• Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales.
• Target start date: As soon as possible.

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

Application Procedure

All applications must include:

1. A motivation letter addressed to Dr. Luis Serrano.
2. A complete CV including contact details.
3. Contact details of two referees.

All applications must be addressed to Dr. Luis Serrano and be submitted online on the "Apply button below".

Selection Process

₋ Pre-selection: The pre-selection process will be based on qualifications and expertise reflected on the candidates CVs. It will be merit-based.

₋ Interview: Preselected candidates will be interviewed by the Hiring Manager of the position and a selection panel if required.

₋ Offer Letter: Once the successful candidate is identified the Human Resources department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.

Deadline: Please submit your application by December 6th, 2021.

Suggestions: The CRG believes in ongoing improvement and promotes a culture of feedback. This is one of the reasons we have in place, at your disposal as a candidate, a mechanism to gather your suggestions/complaints concerning your candidate experience in our recruitment processes. Your feedback really matters to us in our aim at creating a positive candidate journey. You can make a difference and help us improve by letting us know your suggestions through the following form.