Research Trainee
The Institute
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.
In April 2021, the Centre for Genomic Regulation (CRG) received the renewal of the 'HR Excellence in Research' Award from the European Commission. This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code).
The role
We search for a researcher to work in an on-going project analysing paracrine communication in pancreatic ductal adenocarcinoma (PDAC). The researcher will analyse changes in expression, at the RNA and protein levels, of a group of secreted factors identified in secretomic screens using PDAC tumor cells and cancer-associated fibroblast. The tasks will also involve manipulation of signalling pathways by means of inhibitors and lentiviral-mediated transduction of shRNAs and/or protein products. Proven experience in the field of research and experimental techniques is strictly required.
About the lab
The group aims to dissect how the activities of the DYRK family of protein kinases are linked to human pathology. We are particularly interested on DYRK1A and DYRK1B family members and how their associated-activities impact on the regulation of gene expression programs either directly through their recruitment to chromatin or indirectly through modulation of specific signalling pathways in the context of tumor growth.
Whom would we like to hire?
Professional experience
Must Have
-
You have proven experience with mammalian cell culture, including cancer-associated fibroblasts, RT-qPCR, ELISA, Western blot, paracrine assays, immunohistochemistry, handling and preparation of lentiviral stocks
-
You have background knowledge on pancreatic adenocarcinoma
-
You read scientific literature
-
You are fluent in English
Education and training
-
You hold a MSc in aspects related with molecular biology or biomedical research
Languages
-
You are proficient in English
Technical skills
-
Protein analysis: Western blot, ELISA, immunohistochemistry
-
RNA manipulation: preparation, RT-qPCR
-
Mammalian cell culture: transient and stable transfections
-
Handling and preparation of lentiviral strocks
Competences
-
Highly developed organizational skills
-
Ability to work independently
-
Ability to work as part of a team
-
Good communication skills
The Offer – Working Conditions
-
Contract duration: Temporary contract of 4 renewable until 6 months
-
Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales
-
Target start date: As soon as possible.
We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.
We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.
The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.
Application Procedure
All applications must include:
-
A motivation letter addressed to Dr Susana de la Luna
-
A complete CV including contact details.
-
Contact details of two referees.
All applications must be addressed to Dr Susana de la Luna and be submitted online trough the "Apply" button below.
Selection Process
-
Pre-selection: The pre-selection process will be based on qualifications and expertise reflected on the candidates CVS. It will be merit-based.
-
Interview: Preselected candidates will be interviewed by the Hiring Manager of the position and a selection panel if required.
-
Offer Letter: Once the successful candidate is identified the People department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.
Deadline: Please submit your application by January 25, 2025
| Attachment | Size |
|---|---|
 researchtrainee_jobadvert_sdelaluna_012025.pdf | 295.93 KB |
