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Postdoc - Evolution of Genome Regulation

Postdoc - Evolution of Genome Regulation

The Institute

The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.

In September 2026, the Centre for Genomic Regulation (CRG) has received the renewal of the 'HR Excellence in Research' Award from the European Commission. This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code).

Please, check out our Recruitment Policy

The role

We are seeking a highly motivated postdoctoral researcher to investigate the evolution of chromatin states and regulators across eukaryotes. The successful candidate will combine chromatin proteomics, epigenetic drug treatments, and genetic perturbation of candidate chromatin readers-effectors in diverse species. We welcome enthusiastic applicants with a broad interest in evolutionary biology, gene regulation, and/or chromatin biology, and with a solid background in functional genomics.

The work will be part of our ERC-funded project CELL-SYSTEMATICS, which aims at understanding how animal cell type diversity originated and evolve. The candidate will be part of a highly interdisciplinary team that includes developmental, computational, evolutionary and molecular biologists.

References

Navarrete, C. et al. Diversity and evolution of chromatin regulatory states across eukaryotes. Nat Genet 58, 2134–2140 (2026).

Grau-Bové, X. et al. A phylogenetic and proteomic reconstruction of eukaryotic chromatin evolution. Nat Ecol Evol 6, 1007–1023 (2022). 

About the lab

The Sebé-Pedrós lab studies the evolution of cell type programs and genome regulation, combining single-cell genomics, chromatin profiling, and comparative genomics methods in a phylogenetically diverse array of eukaryotes. For more details about the lab, visit the lab website: https://www.sebepedroslab.org/

Whom would we like to hire?

Professional experience

Must Have

  • Experience in chromatin biology (ChIP-seq, ATAC, etc)
  • Experience in basic molecular biology protocols
  • Basic experience in bioinformatics (UNIX environments, R/Python, etc.)

Desirable but not required/ Nice to have

  • Experience in genetic tools in non-model species
  • Experience in molecular phylogenetics and comparative genomics

Education and training

  • A PhD in Biology (or related disciplines)

Languages

  • English fluency.

Competencies

  • Highly developed organization and coordination skills
  • Dedication, motivation, and rigor in scientific pursuits
  • Capacity to work both independently and as part of a team

The Offer – Working Conditions

  • Contract duration: Technical and scientific activities contract linked to the project (estimated duration 2 yesars)
  • Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales
  • Target start date: November 2026

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

Application Procedure

All applications must include:

  1. A complete CV including contact details.
  2. Contact details of two referees.

All applications must be be submitted online through the "Apply" button below.

Selection Process

  • Pre-selection: The pre-selection process will be based on qualifications and expertise reflected on the candidates CVS. It will be merit-based.
  • Interview: Preselected candidates will be interviewed by the Hiring Manager of the position and a selection panel if required.
  • Offer Letter: Once the successful candidate is identified the People department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.

Deadline: Please submit your application by October 29th, 2026.

Suggestions: The CRG believes in ongoing improvement and promotes a culture of feedback. This is one of the reasons we have in place, at your disposal as a candidate, a mechanism to gather your suggestions/complaints concerning your candidate experience in our recruitment processes. Your feedback really matters to us in our aim at creating a positive candidate journey. You can make a difference and help us improve by letting us know your suggestions through the following form.

Project CELL-SYSTEMATICS, grant agreement Nº 101170846

 

 

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